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Title 21

Displaying title 21, up to date as of 7/10/2026. Title 21 was last amended 7/09/2026.
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Title 21Food and DrugsPart / Section
Chapter IFood and Drug Administration, Department of Health and Human Services1 – 1299
Subchapter HMedical Devices800 – 898
Part 872Dental Devices872.1 – 872.6890
Subpart AGeneral Provisions872.1 – 872.9
§ 872.1Scope.
§ 872.3Effective dates of requirement for premarket approval.
§ 872.9Limitations of exemptions from section 510(k) of the Federal Food, Drug, and Cosmetic Act (the act).
Subpart BDiagnostic Devices872.1500 – 872.2060
Subpart C [Reserved]
Subpart DProsthetic Devices872.3060 – 872.3980
Subpart ESurgical Devices872.4120 – 872.4920
Subpart FTherapeutic Devices872.5410 – 872.5590
§ 872.5410Orthodontic appliance and accessories.
§ 872.5470Orthodontic plastic bracket.
§ 872.5500Extraoral orthodontic headgear.
§ 872.5525Preformed tooth positioner.
§ 872.5550Teething ring.
§ 872.5560Electrical salivary stimulatory system.
§ 872.5570Intraoral devices for snoring and intraoral devices for snoring and obstructive sleep apnea.
§ 872.5571Auto titration device for oral appliances.
§ 872.5575Neuromuscular tongue muscle stimulator for the reduction of snoring and obstructive sleep apnea.
§ 872.5580Oral rinse to reduce the adhesion of dental plaque.
§ 872.5590Intraoral cooling device.
Subpart GMiscellaneous Devices872.6010 – 872.6890