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Title 21

Displaying title 21, up to date as of 7/10/2026. Title 21 was last amended 7/09/2026.
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  1. Title 21 —Food and Drugs
  2. Chapter I —Food and Drug Administration, Department of Health and Human Services
  3. Subchapter B —Food for Human Consumption
  4. Part 184 —Direct Food Substances Affirmed as Generally Recognized as Safe
  5. Subpart B   View Full Text
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eCFR Content

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Title 21Food and DrugsPart / Section
Chapter IFood and Drug Administration, Department of Health and Human Services1 – 1299
Subchapter BFood for Human Consumption100 – 199
Part 184Direct Food Substances Affirmed as Generally Recognized as Safe184.1 – 184.1985
Subpart BListing of Specific Substances Affirmed as GRAS184.1005 – 184.1985
§ 184.1005Acetic acid.
§ 184.1007Aconitic acid.
§ 184.1009Adipic acid.
§ 184.1011Alginic acid.
§ 184.1012α-Amylase enzyme preparation from Bacillus stearothermophilus.
§ 184.1021Benzoic acid.
§ 184.1024Bromelain.
§ 184.1025Caprylic acid.
§ 184.1027Mixed carbohydrase and protease enzyme product.
§ 184.1033Citric acid.
§ 184.1034Catalase (bovine liver).
§ 184.1061Lactic acid.
§ 184.1063Enzyme-modified lecithin.
§ 184.1065Linoleic acid.
§ 184.1069Malic acid.
§ 184.1077Potassium acid tartrate.
§ 184.1081Propionic acid.
§ 184.1090Stearic acid.
§ 184.1091Succinic acid.
§ 184.1095Sulfuric acid.
§ 184.1097Tannic acid.
§ 184.1099Tartaric acid.
§ 184.1101Diacetyl tartaric acid esters of mono- and diglycerides.
§ 184.1115Agar-agar.
§ 184.1120Brown algae.
§ 184.1121Red algae.
§ 184.1133Ammonium alginate.
§ 184.1135Ammonium bicarbonate.
§ 184.1137Ammonium carbonate.
§ 184.1138Ammonium chloride.
§ 184.1139Ammonium hydroxide.
§ 184.1140Ammonium citrate, dibasic.
§ 184.1141aAmmonium phosphate, monobasic.
§ 184.1141bAmmonium phosphate, dibasic.
§ 184.1143Ammonium sulfate.
§ 184.1148Bacterially-derived carbohydrase enzyme preparation.
§ 184.1150Bacterially-derived protease enzyme preparation.
§ 184.1155Bentonite.
§ 184.1157Benzoyl peroxide.
§ 184.1165n-Butane and iso-butane.
§ 184.1185Calcium acetate.
§ 184.1187Calcium alginate.
§ 184.1191Calcium carbonate.
§ 184.1193Calcium chloride.
§ 184.1195Calcium citrate.
§ 184.1199Calcium gluconate.
§ 184.1201Calcium glycerophosphate.
§ 184.1205Calcium hydroxide.
§ 184.1206Calcium iodate.
§ 184.1207Calcium lactate.
§ 184.1210Calcium oxide.
§ 184.1212Calcium pantothenate.
§ 184.1221Calcium propionate.
§ 184.1229Calcium stearate.
§ 184.1230Calcium sulfate.
§ 184.1240Carbon dioxide.
§ 184.1245Beta-carotene.
§ 184.1250Cellulase enzyme preparation derived from Trichoderma longibrachiatum.
§ 184.1257Clove and its derivatives.
§ 184.1259Cocoa butter substitute.
§ 184.1260Copper gluconate.
§ 184.1261Copper sulfate.
§ 184.1262Corn silk and corn silk extract.
§ 184.1265Cuprous iodide.
§ 184.1271L-Cysteine.
§ 184.1272L-Cysteine monohydrochloride.
§ 184.1277Dextrin.
§ 184.1278Diacetyl.
§ 184.1282Dill and its derivatives.
§ 184.1287Enzyme-modified fats.
§ 184.1293Ethyl alcohol.
§ 184.1295Ethyl formate.
§ 184.1296Ferric ammonium citrate.
§ 184.1297Ferric chloride.
§ 184.1298Ferric citrate.
§ 184.1301Ferric phosphate.
§ 184.1304Ferric pyrophosphate.
§ 184.1307Ferric sulfate.
§ 184.1307aFerrous ascorbate.
§ 184.1307bFerrous carbonate.
§ 184.1307cFerrous citrate.
§ 184.1307dFerrous fumarate.
§ 184.1308Ferrous gluconate.
§ 184.1311Ferrous lactate.
§ 184.1315Ferrous sulfate.
§ 184.1316Ficin.
§ 184.1317Garlic and its derivatives.
§ 184.1318Glucono delta-lactone.
§ 184.1321Corn gluten.
§ 184.1322Wheat gluten.
§ 184.1323Glyceryl monooleate.
§ 184.1324Glyceryl monostearate.
§ 184.1328Glyceryl behenate.
§ 184.1329Glyceryl palmitostearate.
§ 184.1330Acacia (gum arabic).
§ 184.1333Gum ghatti.
§ 184.1339Guar gum.
§ 184.1343Locust (carob) bean gum.
§ 184.1349Karaya gum (sterculia gum).
§ 184.1351Gum tragacanth.
§ 184.1355Helium.
§ 184.1366Hydrogen peroxide.
§ 184.1370Inositol.
§ 184.1372Insoluble glucose isomerase enzyme preparations.
§ 184.1375Iron, elemental.
§ 184.1386Isopropyl citrate.
§ 184.1387Lactase enzyme preparation from Candida pseudotropicalis.
§ 184.1388Lactase enzyme preparation from Kluyveromyces lactis.
§ 184.1400Lecithin.
§ 184.1408Licorice and licorice derivatives.
§ 184.1409Ground limestone.
§ 184.1415Animal lipase.
§ 184.1420Lipase enzyme preparation derived from Rhizopus niveus.
§ 184.1425Magnesium carbonate.
§ 184.1426Magnesium chloride.
§ 184.1428Magnesium hydroxide.
§ 184.1431Magnesium oxide.
§ 184.1434Magnesium phosphate.
§ 184.1440Magnesium stearate.
§ 184.1443Magnesium sulfate.
§ 184.1443aMalt.
§ 184.1444Maltodextrin.
§ 184.1445Malt syrup (malt extract).
§ 184.1446Manganese chloride.
§ 184.1449Manganese citrate.
§ 184.1452Manganese gluconate.
§ 184.1461Manganese sulfate.
§ 184.1472Menhaden oil.
§ 184.1490Methylparaben.
§ 184.1498Microparticulated protein product.
§ 184.1505Mono- and diglycerides.
§ 184.1521Monosodium phosphate derivatives of mono- and diglycerides.
§ 184.1530Niacin.
§ 184.1535Niacinamide.
§ 184.1537Nickel.
§ 184.1538Nisin preparation.
§ 184.1540Nitrogen.
§ 184.1545Nitrous oxide.
§ 184.1553Peptones.
§ 184.1555Rapeseed oil.
§ 184.1560Ox bile extract.
§ 184.1563Ozone.
§ 184.1583Pancreatin.
§ 184.1585Papain.
§ 184.1588Pectins.
§ 184.1595Pepsin.
§ 184.1610Potassium alginate.
§ 184.1613Potassium bicarbonate.
§ 184.1619Potassium carbonate.
§ 184.1622Potassium chloride.
§ 184.1625Potassium citrate.
§ 184.1631Potassium hydroxide.
§ 184.1634Potassium iodide.
§ 184.1635Potassium iodate.
§ 184.1639Potassium lactate.
§ 184.1643Potassium sulfate.
§ 184.1655Propane.
§ 184.1660Propyl gallate.
§ 184.1666Propylene glycol.
§ 184.1670Propylparaben.
§ 184.1676Pyridoxine hydrochloride.
§ 184.1685Rennet (animal-derived) and chymosin preparation (fermentation-derived).
§ 184.1695Riboflavin.
§ 184.1697Riboflavin-5′-phosphate (sodium).
§ 184.1698Rue.
§ 184.1699Oil of rue.
§ 184.1702Sheanut oil.
§ 184.1721Sodium acetate.
§ 184.1724Sodium alginate.
§ 184.1733Sodium benzoate.
§ 184.1736Sodium bicarbonate.
§ 184.1742Sodium carbonate.
§ 184.1751Sodium citrate.
§ 184.1754Sodium diacetate.
§ 184.1763Sodium hydroxide.
§ 184.1764Sodium hypophosphite.
§ 184.1768Sodium lactate.
§ 184.1769aSodium metasilicate.
§ 184.1784Sodium propionate.
§ 184.1792Sodium sesquicarbonate.
§ 184.1801Sodium tartrate.
§ 184.1804Sodium potassium tartrate.
§ 184.1807Sodium thiosulfate.
§ 184.1835Sorbitol.
§ 184.1845Stannous chloride (anhydrous and dihydrated).
§ 184.1848Starter distillate.
§ 184.1851Stearyl citrate.
§ 184.1854Sucrose.
§ 184.1857Corn sugar.
§ 184.1859Invert sugar.
§ 184.1865Corn syrup.
§ 184.1866High fructose corn syrup.
§ 184.1875Thiamine hydrochloride.
§ 184.1878Thiamine mononitrate.
§ 184.1890α-Tocopherols.
§ 184.1901Triacetin.
§ 184.1903Tributyrin.
§ 184.1911Triethyl citrate.
§ 184.1914Trypsin.
§ 184.1923Urea.
§ 184.1924Urease enzyme preparation from Lactobacillus fermentum.
§ 184.1930Vitamin A.
§ 184.1945Vitamin B12.
§ 184.1950Vitamin D.
§ 184.1973Beeswax (yellow and white).
§ 184.1976Candelilla wax.
§ 184.1978Carnauba wax.
§ 184.1979Whey.
§ 184.1979aReduced lactose whey.
§ 184.1979bReduced minerals whey.
§ 184.1979cWhey protein concentrate.
§ 184.1983Bakers yeast extract.
§ 184.1984Zein.
§ 184.1985Aminopeptidase enzyme preparation derived from lactococcus lactis.
eCFR Content