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e-CFR data is current as of February 23, 2021

Title 21Chapter ISubchapter BPart 170Subpart B → §170.22


Title 21: Food and Drugs
PART 170—FOOD ADDITIVES
Subpart B—Food Additive Safety


§170.22   Safety factors to be considered.

In accordance with section 409(c)(5)(C) of the Act, the following safety factors will be applied in determining whether the proposed use of a food additive will be safe: Except where evidence is submitted which justifies use of a different safety factor, a safety factor in applying animal experimentation data to man of 100 to 1, will be used; that is, a food additive for use by man will not be granted a tolerance that will exceed 1100 th of the maximum amount demonstrated to be without harm to experimental animals.

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